专任教师
牛畅
牛 畅
博士,副教授,硕士生导师
北京市海淀区西三环北路105号888集团电子游戏理科楼
E-mail:niuchang@cnu.edu.cn
研究方向:
肿瘤分子生物学;病原微生物感染宿主和宿主免疫防御的分子机制
教育背景及工作经历:
2018.1-至今 888集团电子游戏 副教授
2013.9-2017.12 888集团电子游戏 讲师
2010.9-2013.7 浙江大学 博士
2007.9-2010.7 军事医学科学院 硕士
2003.9-2007.7 西北农林科技大学 学士
主持项目:
北京市优秀人才培养资助项目(2015-2018)
国家自然科学基金青年项目(2015-2018)
北京市自然科学基金面上项目(2018-2020)
北京市青年拔尖人才培育计划项目(2019-2021)
代表论文:
1. Cheng L#, Yuan B#, Ying S#, Niu C#, Mai H, Guan X, Yang X, Teng Y, Lin J, Huang J, Jin R, Wu J,Liu B, Chang S, Wang E, Zhang C, Hou N, Cheng X, Xu D, Yang X, Gao S, Ye Q. PES1 is a critical component of telomerase assembly and regulates cellular senescence, Science Advances, 2019, 5(5): 0-eaav1090.
2. Niu C#, Wang D#, Liu X#, Liu H, Liu X, Feng E, Pan C, Wang R, Xiao W, Liu X, Liu X, Zhu L, Wang H, An H-NS family protein, Sfh, regulates acid resistance by inhibition of glutamate decarboxylase expression in Shigella flexneri 2457T, Front Microbiol, 2017, 8(10): 1923.
3. Niu C#, Yang J#, Liu H, Cui Y, Xu H, Wang R, Liu X, Feng E, Wang D, Pan C, Xiao W, Liu X, Zhu L, Wang H,Role of the virulence plasmid in acid resistance of Shigella flexneri,Sci Rep,2017,25(4): 46465.
4. Niu C#,Shang N#,Liao X#,Feng E,Liu X,Wang D,Wang J,Huang P,Hua Y,Zhu L,Wang H,Analysis of soluble protein complexes in Shigella flexneri reveal the influence of temperature on the expression of lipopolysaccharide,Mol Cell Proteomics,2013,12(5): 1250-1258.
5. Niu C#,Yan Z#,Cheng L#,Zhu J,Zhang H,Xu X,Lin J,Ye Q,Downregulation and antiproliferative role of FHL3 in breast cancer,IUBMB Life,2012,63(9): 764-771.
6. Niu C#,Liang C#,Guo J#,Cheng L,Zhang H,Qin X,Zhang Q,Ding L,Yuan B,Xu X,Li J,Lin J,Ye Q,Downregulation and growth inhibitory role of FHL1 in lung cancer,Int J Cancer,2011,130(11):2549-2556.
7. Ding L#,Niu C#,Zheng Y#,Xiong Z,Liu Y,Lin J,Sun H,Huang K,Yang W,Li X,Ye Q,FHL1 interacts with oestrogen receptors and regulates breast cancer cell growth,J Cell Mol Med,2011,15(1):72-85.
8. Cheng L#,Li J#,Han Y,Lin J,Niu C,Zhou Z,Yuan B,Huang K,Li J,Jiang K,Zhang H,Ding L,Xu X,Ye Q,PES1 promotes breast cancer by differentially regulating ERα and ERβ,J Clin Invest,2012,122(8):2857-2870.